Highlighting Platelets in Prediabetes

Zibusiso Mkandla is a young academic who was born in a small district hospital in Murewa, Zimbabwe. Through a scholarship, he was fortunate enough to study for a Biomedical Technology degree in South Africa. He then furthered his studies with an MSc of the same name, and recently completed a PhD in Physiology, supervised by Dr Bongani Nkambule (DRILL Fellow). This study was part of a larger study on immune modulation in prediabetes, where he focused on the platelet function. In summary, his study highlighted the synergistic effect of dual metformin and low-dose aspirin therapy in modulating platelet function in prediabetes. It also pointed out the shortcomings of monotherapy antiplatelet treatment influenced by the multiple signalling pathways associated with platelet activation.

L to R: Dr Zibusiso Mkandla with PhD supervisor Dr Bongani Nkambule (DRILL Fellow)

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